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Cellular ras gene activity is required for full neoplastic transformation by polyomavirus.

To investigate the role of ras gene activity in cellular transformation by polyomavirus, murine C3H10T1/2 cells were rendered ras deficient by transfection with an antisense ras gene construct. Ras deficiency resulted in a partial suppression of the polyomavirus-induced transformed phenotype. The pr...

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Autori principali: Raptis, L, Marcellus, R, Corbley, M J, Krook, A, Whitfield, J, Anderson, S K, Haliotis, T
Natura: Artigo
Lingua:Inglês
Pubblicazione: 1991
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC248998/
https://ncbi.nlm.nih.gov/pubmed/1654439
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