Cellular ras gene activity is required for full neoplastic transformation by polyomavirus.
To investigate the role of ras gene activity in cellular transformation by polyomavirus, murine C3H10T1/2 cells were rendered ras deficient by transfection with an antisense ras gene construct. Ras deficiency resulted in a partial suppression of the polyomavirus-induced transformed phenotype. The pr...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1991
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1654439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5203-5210.1991 |
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