Cellular ras gene activity is required for full neoplastic transformation by polyomavirus.

To investigate the role of ras gene activity in cellular transformation by polyomavirus, murine C3H10T1/2 cells were rendered ras deficient by transfection with an antisense ras gene construct. Ras deficiency resulted in a partial suppression of the polyomavirus-induced transformed phenotype. The pr...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Virol
Huvudupphovsmän: Raptis, L, Marcellus, R, Corbley, M J, Krook, A, Whitfield, J, Anderson, S K, Haliotis, T
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 1991
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248998/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1654439/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5203-5210.1991
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