Cellular ras gene activity is required for full neoplastic transformation by polyomavirus.

To investigate the role of ras gene activity in cellular transformation by polyomavirus, murine C3H10T1/2 cells were rendered ras deficient by transfection with an antisense ras gene construct. Ras deficiency resulted in a partial suppression of the polyomavirus-induced transformed phenotype. The pr...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Raptis, L, Marcellus, R, Corbley, M J, Krook, A, Whitfield, J, Anderson, S K, Haliotis, T
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1991
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248998/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1654439/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.65.10.5203-5210.1991
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