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Carcinogen-induced loss of heterozygosity at the Aprt locus in somatic cells of the mouse

Genetic events leading to the loss of heterozygosity (LOH) have been shown to play a crucial role in the development of cancer. However, LOH events do not occur only in genetically unstable cancer cells but also have been detected in normal somatic cells of mouse and man. Mice, in which one of the a...

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Autors principals: Wijnhoven, Susan W. P., Van Sloun, Petra P. H., Kool, Hanneke J. M., Weeda, Geert, Slater, Rosalyn, Lohman, Paul H. M., van Zeeland, Albert A., Vrieling, Harry
Format: Artigo
Idioma:Inglês
Publicat: The National Academy of Sciences 1998
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC24893/
https://ncbi.nlm.nih.gov/pubmed/9811874
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