Carcinogen-induced loss of heterozygosity at the Aprt locus in somatic cells of the mouse

Genetic events leading to the loss of heterozygosity (LOH) have been shown to play a crucial role in the development of cancer. However, LOH events do not occur only in genetically unstable cancer cells but also have been detected in normal somatic cells of mouse and man. Mice, in which one of the a...

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發表在:	Proc Natl Acad Sci U S A
Principais autores:	Wijnhoven, Susan W. P., Van Sloun, Petra P. H., Kool, Hanneke J. M., Weeda, Geert, Slater, Rosalyn, Lohman, Paul H. M., van Zeeland, Albert A., Vrieling, Harry
格式:	Artigo
語言:	Inglês
出版:	National Academy of Sciences 1998
主題:	Biological Sciences
在線閱讀:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24893/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811874/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.23.13759
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