The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage.

In this study the role of nucleotide excision repair (NER) in protecting mouse embryonic stem (ES) cells against the genotoxic effects of UV-photolesions was analysed. Repair of cyclobutane pyrimidine dimers (CPD) in transcribed genes could not be detected whereas the removal of (6-4) photoproducts...

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Detalhes bibliográficos
Main Authors: Van Sloun, P P, Jansen, J G, Weeda, G, Mullenders, L H, van Zeeland, A A, Lohman, P H, Vrieling, H
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148560/
https://ncbi.nlm.nih.gov/pubmed/10454634
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