The role of nucleotide excision repair in protecting embryonic stem cells from genotoxic effects of UV-induced DNA damage.

In this study the role of nucleotide excision repair (NER) in protecting mouse embryonic stem (ES) cells against the genotoxic effects of UV-photolesions was analysed. Repair of cyclobutane pyrimidine dimers (CPD) in transcribed genes could not be detected whereas the removal of (6-4) photoproducts...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Van Sloun, P P, Jansen, J G, Weeda, G, Mullenders, L H, van Zeeland, A A, Lohman, P H, Vrieling, H
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1999
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148560/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454634/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.16.3276
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