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Silencing of Mouse Aprt Is a Gradual Process in Differentiated Cells

Mouse Aprt constructs that are highly susceptible to DNA methylation-associated inactivation in embryonal carcinoma cells were transfected into differentiated cells, where they were expressed. Construct silencing was induced by either whole-cell fusion of the expressing differentiated cells with emb...

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Detalhes bibliográficos
Main Authors: Yates, Phillip A., Burman, Robert, Simpson, James, Ponomoreva, Olga N., Thayer, Mathew J., Turker, Mitchell S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2003
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC164859/
https://ncbi.nlm.nih.gov/pubmed/12808089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.13.4461-4470.2003
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