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Association of a CYP4A11 Variant and Blood Pressure in Black Men
CYP4A11 arachidonic acid monooxygenase oxidizes endogenous arachidonic acid to 20-hydroxyeicosatetraenoic acid, a renal vasoconstrictor and natriuretic. Cyp4a deficiency causes hypertension in male mice, and a loss-of-function variant (T8590C) of CYP4A11 is associated with hypertension in white indi...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society of Nephrology
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2488260/ https://ncbi.nlm.nih.gov/pubmed/18385420 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008010063 |
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