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Association of a CYP4A11 Variant and Blood Pressure in Black Men

CYP4A11 arachidonic acid monooxygenase oxidizes endogenous arachidonic acid to 20-hydroxyeicosatetraenoic acid, a renal vasoconstrictor and natriuretic. Cyp4a deficiency causes hypertension in male mice, and a loss-of-function variant (T8590C) of CYP4A11 is associated with hypertension in white indi...

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Detalhes bibliográficos
Main Authors: Gainer, James V., Lipkowitz, Michael S., Yu, Chang, Waterman, Michael R., Dawson, Elliott P., Capdevila, Jorge H., Brown, Nancy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488260/
https://ncbi.nlm.nih.gov/pubmed/18385420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2008010063
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