The T8590C Polymorphism of CYP4A11 and 20-Hydroxyeicosatetraenoic Acid in Essential Hypertension

A role for a deficit in transport actions of 20-hydroxyeicosatetraenoic acid (20-HETE) in hypertension is supported by the following: (1) diminished renal 20-HETE in Dahl-S rats; (2) altered salt- and furosemide-induced 20-HETE responses in salt-sensitive hypertensive subjects; and (3) increased pop...

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Main Authors: Laffer, Cheryl L., Gainer, James V., Waterman, Michael R., Capdevila, Jorge H., Laniado-Schwartzman, Michal, Nasjletti, Alberto, Brown, Nancy J., Elijovich, Fernando
Format: Artigo
Jezik:Inglês
Izdano: 2008
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2365894/
https://ncbi.nlm.nih.gov/pubmed/18227405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/HYPERTENSIONAHA.107.102921
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