CYP4A11 variant is associated with high density lipoprotein cholesterol in women

The ω-hydroxylase CYP4A11 catalyzes the transformation of epoxyeicosatrienoic acids to omega-hydroxylated-epoxyeicosatrienoic acids, endogenous peroxisome proliferator-activated receptor α (PPARα) agonists. PPARα activation increases high-density lipoprotein-cholesterol (HDL-C). A cytosine-for-thymi...

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Bibliographische Detailangaben
Hauptverfasser: White, Charles C., Feng, QiPing, Cupples, L. Adrienne, Gainer, James V., Dawson, Elliott P., Wilke, Russell A., Brown, Nancy J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2011
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3380161/
https://ncbi.nlm.nih.gov/pubmed/21912424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/tpj.2011.40
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