Rooted in risk: genetic predisposition for low-density lipoprotein cholesterol level associates with diminished low-density lipoprotein cholesterol response to statin treatment

AIMS: To utilize previously reported lead SNPs for low-density lipoprotein cholesterol (LDL-c) levels to find additional loci of importance to statin response, and examine whether genetic predisposition to LDL-c levels associates with differential statin response. METHODS: We investigated effects on...

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Detalhes bibliográficos
Publicado no:Pharmacogenomics
Main Authors: Smit, Roelof AJ, Postmus, Iris, Trompet, Stella, Barnes, Michael R, Warren, Helen, Arsenault, Benoit J, Chasman, Daniel I, Cupples, L Adrienne, Hitman, Graham A, Krauss, Ronald M, Li, Xiaohui, Psaty, Bruce M, Stein, Charles M, Rotter, Jerome I, Jukema, J Wouter
Formato: Artigo
Idioma:Inglês
Publicado em: Future Medicine Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5558541/
https://ncbi.nlm.nih.gov/pubmed/27648687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/pgs-2016-0091
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