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The Use of Steroid Sulfatase Inhibitors as a Novel Therapeutic Strategy Against Hormone-Dependent Endometrial Cancer

The past few years have seen an increase in the reported incidence of endometrial carcinoma, one of the most frequently diagnosed malignancies of the female genital tract. Estrogen production is vital for the mitogenesis of endometrial tumors. Inhibition of steroid sulfatase (STS), an enzyme respons...

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Главные авторы: Foster, Paul A., Woo, L. W. Lawrence, Potter, Barry V. L., Reed, Michael J., Purohit, Atul
Формат: Artigo
Язык:Inglês
Опубликовано: The Endocrine Society 2008
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488239/
https://ncbi.nlm.nih.gov/pubmed/18450955
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0223
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