Aromatase and Dual Aromatase-Steroid Sulfatase Inhibitors from the Letrozole and Vorozole Templates

Concurrent inhibition of aromatase and steroid sulfatase (STS) may provide a more effective treatment for hormone-dependent breast cancer than monotherapy against individual enzymes, and several dual aromatase–sulfatase inhibitors (DASIs) have been reported. Three aromatase inhibitors with sub-nanom...

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Detalhes bibliográficos
Main Authors: Wood, Paul M, Woo, L W Lawrence, Thomas, Mark P, Mahon, Mary F, Purohit, Atul, Potter, Barry V L
Formato: Artigo
Idioma:Inglês
Publicado em: WILEY-VCH Verlag 2011
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Full Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3170879/
https://ncbi.nlm.nih.gov/pubmed/21608133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201100145
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