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7B2 Prevents Unfolding and Aggregation of Prohormone Convertase 2

Prohormone convertase 2 (PC2) requires interaction with the neuroendocrine protein 7B2 for the production of an activatable zymogen; the mechanism for this effect is unknown. 7B2 could act proactively to generate an activation-competent form of pro-PC2 during synthesis, or block spontaneous generati...

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Autori principali: Lee, Sang-Nam, Lindberg, Iris
Natura: Artigo
Lingua:Inglês
Pubblicazione: The Endocrine Society 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488232/
https://ncbi.nlm.nih.gov/pubmed/18467442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2008-0064
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