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Hepatitis B virus transactivator X protein is not tumorigenic in transgenic mice.

The hepatitis B virus X protein acts as a transcriptional transactivator in vitro. To elucidate possible biological effects of X protein on liver cells in vivo, we generated four lines of transgenic mice carrying the X gene open reading frame under the control of the human alpha-1-antitrypsin regula...

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Dettagli Bibliografici
Pubblicato in:J Virol
Autori principali: Lee, T H, Finegold, M J, Shen, R F, DeMayo, J L, Woo, S L, Butel, J S
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 1990
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC248767/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2243380/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.12.5939-5947.1990
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