Hepatitis B Virus X Protein Acts as a Tumor Promoter in Development of Diethylnitrosamine-Induced Preneoplastic Lesions

Chronic infection with hepatitis B virus (HBV) is one of the major etiological factors in the development of human hepatocellular carcinoma. Transgenic mice that express the HBV X protein (HBx) have previously been shown to be more sensitive to the effects of hepatocarcinogens. Although the mechanis...

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Main Authors: Madden, Charles R., Finegold, Milton J., Slagle, Betty L.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC114876/
https://ncbi.nlm.nih.gov/pubmed/11264374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.8.3851-3858.2001
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