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Hepatitis B virus transactivator X protein is not tumorigenic in transgenic mice.

The hepatitis B virus X protein acts as a transcriptional transactivator in vitro. To elucidate possible biological effects of X protein on liver cells in vivo, we generated four lines of transgenic mice carrying the X gene open reading frame under the control of the human alpha-1-antitrypsin regula...

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Main Authors: Lee, T H, Finegold, M J, Shen, R F, DeMayo, J L, Woo, S L, Butel, J S
Formato: Artigo
Idioma:Inglês
Publicado: 1990
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC248767/
https://ncbi.nlm.nih.gov/pubmed/2243380
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