Oncogene-dependent apoptosis is mediated by caspase-9

Understanding how oncogenic transformation sensitizes cells to apoptosis may provide a strategy to kill tumor cells selectively. We previously developed a cell-free system that recapitulates oncogene dependent apoptosis as reflected by activation of caspases, the core of the apoptotic machinery. Her...

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Bibliografiske detaljer

Udgivet i:	Proc Natl Acad Sci U S A
Principais autores:	Fearnhead, Howard O., Rodriguez, Joe, Govek, Eve-Ellen, Guo, Wenjun, Kobayashi, Ryuji, Hannon, Greg, Lazebnik, Yuri A.
Format:	Artigo
Sprog:	Inglês
Udgivet:	National Academy of Sciences 1998
Fag:	Biological Sciences
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24876/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811857/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.23.13664
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