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Identification and Structural Characterization of a CBP/p300-Binding Domain from the ETS Family Transcription Factor GABPα
Using NMR spectroscopy we identified and characterized a previously unrecognized structured domain near the N-terminus (residues 35−121) of the ETS family transcription factor GABPα. The monomeric domain folds as a 5-stranded β-sheet crossed by a distorted helix. Although globally resembling ubiquit...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2486348/ https://ncbi.nlm.nih.gov/pubmed/18295234 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.01.054 |
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