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Oncogenesis by sequestration of CBP/p300 in transcriptionally inactive hyperacetylated chromatin domains
In a subset of poorly differentiated and highly aggressive carcinoma, a chromosomal translocation, t(15;19)(q13;p13), results in an in-frame fusion of the double bromodomain protein, BRD4, with a testis-specific protein of unknown function, NUT (nuclear protein in testis). In this study, we show tha...
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Main Authors: | , , , , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944051/ https://ncbi.nlm.nih.gov/pubmed/20676058 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2010.176 |
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