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Induction of a pro-apoptotic ATM–NF-κB pathway and its repression by ATR in response to replication stress
The transcription factor NF-κB has critical functions in biologic responses to genotoxic stimuli. Activation of NF-κB in response to DNA double strand break (DSB) inducers can be mediated by ATM (ataxia telangiectasia mutated)-dependent phosphorylation of NEMO (NF-κB essential modulator). Here, we s...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2486281/ https://ncbi.nlm.nih.gov/pubmed/18583959 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2008.127 |
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