Crystallization of protein–ligand complexes

Obtaining diffraction-quality crystals has long been a bottleneck in solving the three-dimensional structures of proteins. Often proteins may be stabilized when they are complexed with a substrate, nucleic acid, cofactor or small molecule. These ligands, on the other hand, have the potential to indu...

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Detalhes bibliográficos
Main Authors: Hassell, Anne M., An, Gang, Bledsoe, Randy K., Bynum, Jane M., Carter, H. Luke, Deng, Su-Jun J., Gampe, Robert T., Grisard, Tamara E., Madauss, Kevin P., Nolte, Robert T., Rocque, Warren J., Wang, Liping, Weaver, Kurt L., Williams, Shawn P., Wisely, G. Bruce, Xu, Robert, Shewchuk, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483499/
https://ncbi.nlm.nih.gov/pubmed/17164529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444906047020
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