Crystallization of protein–ligand complexes

Obtaining diffraction-quality crystals has long been a bottleneck in solving the three-dimensional structures of proteins. Often proteins may be stabilized when they are complexed with a substrate, nucleic acid, cofactor or small molecule. These ligands, on the other hand, have the potential to indu...

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Hlavní autoři: Hassell, Anne M., An, Gang, Bledsoe, Randy K., Bynum, Jane M., Carter, H. Luke, Deng, Su-Jun J., Gampe, Robert T., Grisard, Tamara E., Madauss, Kevin P., Nolte, Robert T., Rocque, Warren J., Wang, Liping, Weaver, Kurt L., Williams, Shawn P., Wisely, G. Bruce, Xu, Robert, Shewchuk, Lisa M.
Médium: Artigo
Jazyk:Inglês
Vydáno: International Union of Crystallography 2007
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2483499/
https://ncbi.nlm.nih.gov/pubmed/17164529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S0907444906047020
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