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Src family kinase mediated negative regulation of hematopoietic stem cell mobilization involves both intrinsic and microenvironmental factors
OBJECTIVE: The intracellular signals that contribute to G-CSF receptor induced stem cell mobilization are poorly characterized. METHODS: We show enhanced G-CSF induced mobilization of stem cells in mice deficient in the expression of Src family kinases (SFK−/−), which is associated with hypersensiti...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2481405/ https://ncbi.nlm.nih.gov/pubmed/17588471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2007.03.017 |
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