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Bubbles, Gating, and Anesthetics in Ion Channels
We suggest that bubbles are the bistable hydrophobic gates responsible for the on-off transitions of single channel currents. In this view, many types of channels gate by the same physical mechanism—dewetting by capillary evaporation—but different types of channels use different sensors to modulate...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
The Biophysical Society
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2480679/ https://ncbi.nlm.nih.gov/pubmed/18234836 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.120493 |
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