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Bubbles, Gating, and Anesthetics in Ion Channels

We suggest that bubbles are the bistable hydrophobic gates responsible for the on-off transitions of single channel currents. In this view, many types of channels gate by the same physical mechanism—dewetting by capillary evaporation—but different types of channels use different sensors to modulate...

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書誌詳細
主要な著者: Roth, Roland, Gillespie, Dirk, Nonner, Wolfgang, Eisenberg, Robert E.
フォーマット: Artigo
言語:Inglês
出版事項: The Biophysical Society 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480679/
https://ncbi.nlm.nih.gov/pubmed/18234836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.120493
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