Llwytho...

Bubbles, Gating, and Anesthetics in Ion Channels

We suggest that bubbles are the bistable hydrophobic gates responsible for the on-off transitions of single channel currents. In this view, many types of channels gate by the same physical mechanism—dewetting by capillary evaporation—but different types of channels use different sensors to modulate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Roth, Roland, Gillespie, Dirk, Nonner, Wolfgang, Eisenberg, Robert E.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Biophysical Society 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2480679/
https://ncbi.nlm.nih.gov/pubmed/18234836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.120493
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