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Permeation Properties of an Engineered Bacterial OmpF Porin Containing the EEEE-Locus of Ca(2+) Channels
The selectivity filter of the bacterial porin OmpF carries a small net charge close to −1 e and is therefore only slightly cation-selective. Calcium channels, on the other hand, contain four negatively charged glutamates, the EEEE-locus, and are among the most selective cation channels known. We aim...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Biophysical Society
2004
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1304784/ https://ncbi.nlm.nih.gov/pubmed/15326033 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.104.041384 |
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