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Chemical Modification of the Bacterial Porin OmpF: Gain of Selectivity by Volume Reduction

OmpF is an essentially nonselective porin isolated from the outer membrane of Escherichia coli. Here we report on the manipulation of the ion selectivity of OmpF by chemical modification with MTS reagents (MTSET, MTSEA, and MTSES) and the (rather bulky) tripeptide glutathione, all cysteine specific....

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Detalhes bibliográficos
Main Authors: Vrouenraets, Maarten, Wierenga, Jenny, Meijberg, Wim, Miedema, Henk
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1367271/
https://ncbi.nlm.nih.gov/pubmed/16299071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.072298
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