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Interaction of Zwitterionic Penicillins with the OmpF Channel Facilitates Their Translocation
To study translocation of β-lactam antibiotics of different size and charge across the outer bacterial membrane, we combine an analysis of ion currents through single trimeric outer membrane protein F (OmpF) porins in planar lipid bilayers with molecular dynamics simulations. Because the size of pen...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Biophysical Society
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1367313/ https://ncbi.nlm.nih.gov/pubmed/16339889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.075192 |
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