Mapping of mutations associated with neurovirulence in monkeys infected with Sabin 1 poliovirus revertants selected at high temperature.

Poliovirus type 1 neurovirulence is difficult to analyze because of the 56 mutations which differentiate the neurovirulent Mahoney strain from the attenuated Sabin strain. We have isolated four neurovirulent mutants which differ from the temperature-sensitive parental Sabin 1 strain by only a few mu...

Полное описание

Библиографические подробности

Опубликовано в::	J Virol
Главные авторы:	Christodoulou, C, Colbere-Garapin, F, Macadam, A, Taffs, L F, Marsden, S, Minor, P, Horaud, F
Формат:	Artigo
Язык:	Inglês
Опубликовано:	American Society for Microbiology (ASM) 1990
Предметы:	Research Article
Online-ссылка:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247983/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2168976/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.10.4922-4929.1990
Метки:	Добавить метку Нет меток, Требуется 1-ая метка записи!