Temperature-sensitive poliovirus mutant fails to cleave VP0 and accumulates provirions.

A temperature-sensitive mutant of poliovirus, VP2-103, was isolated and characterized. A single nucleotide change, resulting in the substitution of glutamine for arginine at amino acid 76 of the capsid protein VP2, prevented the maturation of virions at the nonpermissive temperature. Particles indis...

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Bibliografske podrobnosti

izdano v:	J Virol
Principais autores:	Compton, S R, Nelsen, B, Kirkegaard, K
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 1990
Teme:	Research Article
Online dostop:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2166805/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.9.4067-4075.1990
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