Temperature-sensitive poliovirus mutant fails to cleave VP0 and accumulates provirions.
A temperature-sensitive mutant of poliovirus, VP2-103, was isolated and characterized. A single nucleotide change, resulting in the substitution of glutamine for arginine at amino acid 76 of the capsid protein VP2, prevented the maturation of virions at the nonpermissive temperature. Particles indis...
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| Publicado no: | J Virol |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
1990
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC247868/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2166805/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.64.9.4067-4075.1990 |
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