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Temperature-sensitive poliovirus mutant fails to cleave VP0 and accumulates provirions.

A temperature-sensitive mutant of poliovirus, VP2-103, was isolated and characterized. A single nucleotide change, resulting in the substitution of glutamine for arginine at amino acid 76 of the capsid protein VP2, prevented the maturation of virions at the nonpermissive temperature. Particles indis...

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Bibliografski detalji
Glavni autori: Compton, S R, Nelsen, B, Kirkegaard, K
Format: Artigo
Jezik:Inglês
Izdano: 1990
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC247868/
https://ncbi.nlm.nih.gov/pubmed/2166805
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