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Immediate-early regulatory gene mutants define different stages in the establishment and reactivation of herpes simplex virus latency.

Using nonsense and deletion mutants of herpes simplex virus type 1, we investigated the roles of three immediate-early proteins (ICP4, ICP27 and ICP0) in the establishment and reactivation of ganglionic latency in a mouse ocular model. DNA hybridization, superinfection-rescue, and cocultivation tech...

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書誌詳細
主要な著者: Leib, D A, Coen, D M, Bogard, C L, Hicks, K A, Yager, D R, Knipe, D M, Tyler, K L, Schaffer, P A
フォーマット: Artigo
言語:Inglês
出版事項: 1989
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC247748/
https://ncbi.nlm.nih.gov/pubmed/2536101
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