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The promoter of the latency-associated transcripts of herpes simplex virus type 1 contains a functional cAMP-response element: role of the latency-associated transcripts and cAMP in reactivation of viral latency.

A 203-base-pair sequence 5' of the latency-associated transcripts (LATs) of herpes simplex virus type 1 contains a 7-base consensus sequence TGCGTCA that is identical to the cAMP-response element of the proenkephalin gene. This consensus sequence is at -38 relative to the putative 5' end of the LATs...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Leib, D A, Nadeau, K C, Rundle, S A, Schaffer, P A
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1991
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC50745/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1846042/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.88.1.48
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