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The Structure of α-Parvin CH2-Paxillin LD1 Complex Reveals a Novel Modular Recognition for Focal Adhesion Assembly

α-Parvin is an essential component of focal adhesions (FAs), which are large multiprotein complexes that link the plasma membrane and actin cytoskeleton. α-Parvin contains two calponin homology (CH) domains and its C-terminal CH2 domain binds multiple targets including paxillin LD motifs for regulat...

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Detalhes bibliográficos
Main Authors: Wang, Xiaoxia, Fukuda, Koichi, Byeon, In-Ja, Velyvis, Algirdas, Wu, Chuanyue, Gronenborn, Angela, Qin, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475713/
https://ncbi.nlm.nih.gov/pubmed/18508764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M801270200
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