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The pseudo-active site of ILK is essential for its binding to α-parvin and localization to focal adhesions
Integrin-linked kinase (ILK) plays a pivotal role in connecting transmembrane receptor integrin to the actin cytoskeleton and thereby regulating diverse cell adhesion-dependent processes. The kinase domain (KD) of ILK is indispensable for its function, but the underlying molecular basis remains enig...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2796127/ https://ncbi.nlm.nih.gov/pubmed/20005845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.11.028 |
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