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A Ubiquitin-Proteasome Pathway for the Repair of Topoisomerase I-DNA Covalent Complexes
Reversible topoisomerase I (Top1)-DNA cleavage complexes are the key DNA lesion induced by anticancer camptothecins (e.g. topotecan and irinotecan) as well as structurally perturbed DNAs (e.g. oxidatively damaged DNA, UV-irradiated DNA, alkylated DNA, uracil-substituted DNA, mismatched DNA, gapped a...
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| Hlavní autoři: | , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
American Society for Biochemistry and Molecular Biology
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2475699/ https://ncbi.nlm.nih.gov/pubmed/18515798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803493200 |
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