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Control of Translocation through the Sec61 Translocon by Nascent Polypeptide Structure within the Ribosome

During polytopic protein biogenesis, multiple transmembrane segments (TMs) must pass through the ribosome exit tunnel and into the Sec61 translocon prior to insertion into the endoplasmic reticulum membrane. To investigate how movement of a newly synthesized TM along this integration pathway might b...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Daniel, Colin J., Conti, Brian, Johnson, Arthur E., Skach, William R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2475691/
https://ncbi.nlm.nih.gov/pubmed/18480044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803517200
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