IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver

Inflammatory destruction of intrahepatic bile ducts is a common cause of vanishing bile duct syndrome and cholestasis, often progressing to biliary cirrhosis and liver failure. However, the molecular mechanisms underlying the pathogenesis of inflammatory biliary disease are poorly understood. Here,...

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Main Authors: Luedde, Tom, Heinrichsdorff, Jan, de Lorenzi, Rossana, De Vos, Rita, Roskams, Tania, Pasparakis, Manolis
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2008
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474544/
https://ncbi.nlm.nih.gov/pubmed/18606991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800198105
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