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Targeted ablation of IKK2 improves skeletal muscle strength, maintains mass, and promotes regeneration
NF-κB is a major pleiotropic transcription factor modulating immune, inflammatory, cell survival, and proliferative responses, yet the relevance of NF-κB signaling in muscle physiology and disease is less well documented. Here we show that muscle-restricted NF-κB inhibition in mice, through targeted...
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| Główni autorzy: | , , , , , , , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
American Society for Clinical Investigation
2006
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1626136/ https://ncbi.nlm.nih.gov/pubmed/17080195 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI28721 |
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