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IKK1 and IKK2 cooperate to maintain bile duct integrity in the liver

Inflammatory destruction of intrahepatic bile ducts is a common cause of vanishing bile duct syndrome and cholestasis, often progressing to biliary cirrhosis and liver failure. However, the molecular mechanisms underlying the pathogenesis of inflammatory biliary disease are poorly understood. Here,...

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Bibliographische Detailangaben
Hauptverfasser: Luedde, Tom, Heinrichsdorff, Jan, de Lorenzi, Rossana, De Vos, Rita, Roskams, Tania, Pasparakis, Manolis
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2474544/
https://ncbi.nlm.nih.gov/pubmed/18606991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800198105
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