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Halothane modulation of skeletal muscle ryanodine receptors: dependence on Ca(2+), Mg(2+) and ATP
Malignant hyperthermia (MH) susceptibility is a genetic disorder of skeletal muscle associated with mutations in the ryanodine receptor isoform 1 (RyR1) of sarcoplasmic reticulum (SR). In MH-susceptible skeletal fibers, RyR1-mediated Ca(2+) release is highly sensitive to activation by the volatile a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2465464/ https://ncbi.nlm.nih.gov/pubmed/18305228 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.90642.2007 |
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