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Halothane modulation of skeletal muscle ryanodine receptors: dependence on Ca(2+), Mg(2+) and ATP

Malignant hyperthermia (MH) susceptibility is a genetic disorder of skeletal muscle associated with mutations in the ryanodine receptor isoform 1 (RyR1) of sarcoplasmic reticulum (SR). In MH-susceptible skeletal fibers, RyR1-mediated Ca(2+) release is highly sensitive to activation by the volatile a...

詳細記述

保存先:
書誌詳細
主要な著者: Diaz-Sylvester, Paula L., Porta, Maura, Copello, Julio A.
フォーマット: Artigo
言語:Inglês
出版事項: 2008
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465464/
https://ncbi.nlm.nih.gov/pubmed/18305228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.90642.2007
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