Coupled gating of skeletal muscle ryanodine receptors is modulated by Ca(2+), Mg(2+), and ATP

Coupled gating (synchronous openings and closures) of groups of skeletal muscle ryanodine receptors (RyR1), which mimics RyR1-mediated Ca(2+) release underlying Ca(2+) sparks, was first described by Marx et al. (Marx SO, Ondrias K, Marks AR. Science 281: 818–821, 1998). The nature of the RyR1-RyR1 i...

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Bibliographic Details
Main Authors: Porta, Maura, Diaz-Sylvester, Paula L., Neumann, Jake T., Escobar, Ariel L., Fleischer, Sidney, Copello, Julio A.
Format: Artigo
Language:Inglês
Published: American Physiological Society 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3468351/
https://ncbi.nlm.nih.gov/pubmed/22785120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00150.2012
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