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Entropy-Driven Folding of an RNA Helical Junction: An Isothermal Titration Calorimetric Analysis of the Hammerhead Ribozyme

Helical junctions are extremely common motifs in naturally occurring RNAs, but little is known about the thermodynamics that drive their folding. Studies of junction folding face several challenges: non-two-state folding behavior, superposition of secondary and tertiary structural energetics, and dr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Mikulecky, Peter J., Takach, Jennifer C., Feig, Andrew L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465462/
https://ncbi.nlm.nih.gov/pubmed/15134461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0360657
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