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Entropy-Driven Folding of an RNA Helical Junction: An Isothermal Titration Calorimetric Analysis of the Hammerhead Ribozyme

Helical junctions are extremely common motifs in naturally occurring RNAs, but little is known about the thermodynamics that drive their folding. Studies of junction folding face several challenges: non-two-state folding behavior, superposition of secondary and tertiary structural energetics, and dr...

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Detalhes bibliográficos
Main Authors: Mikulecky, Peter J., Takach, Jennifer C., Feig, Andrew L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465462/
https://ncbi.nlm.nih.gov/pubmed/15134461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0360657
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