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Heat capacity changes in RNA folding: application of perturbation theory to hammerhead ribozyme cold denaturation
In proteins, empirical correlations have shown that changes in heat capacity (ΔC(P)) scale linearly with the hydrophobic surface area buried upon folding. The influence of ΔC(P) on RNA folding has been widely overlooked and is poorly understood. In addition to considerations of solvent reorganizatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC506808/ https://ncbi.nlm.nih.gov/pubmed/15282329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkh723 |
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