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Heat capacity changes in RNA folding: application of perturbation theory to hammerhead ribozyme cold denaturation

In proteins, empirical correlations have shown that changes in heat capacity (ΔC(P)) scale linearly with the hydrophobic surface area buried upon folding. The influence of ΔC(P) on RNA folding has been widely overlooked and is poorly understood. In addition to considerations of solvent reorganizatio...

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Pubblicato in:Nucleic Acids Res
Autori principali: Mikulecky, Peter J., Feig, Andrew L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2004
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC506808/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15282329/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/gkh723
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