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Entropy-Driven Folding of an RNA Helical Junction: An Isothermal Titration Calorimetric Analysis of the Hammerhead Ribozyme

Helical junctions are extremely common motifs in naturally occurring RNAs, but little is known about the thermodynamics that drive their folding. Studies of junction folding face several challenges: non-two-state folding behavior, superposition of secondary and tertiary structural energetics, and dr...

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Библиографические подробности
Главные авторы: Mikulecky, Peter J., Takach, Jennifer C., Feig, Andrew L.
Формат: Artigo
Язык:Inglês
Опубликовано: 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2465462/
https://ncbi.nlm.nih.gov/pubmed/15134461
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi0360657
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