UMF-078: A modified flubendazole with potent macrofilaricidal activity against Onchocerca ochengi in African cattle

BACKGROUND: Human onchocerciasis or river blindness, caused by the filarial nematode Onchocerca volvulus, is currently controlled using the microfilaricidal drug, ivermectin. However, ivermectin does not kill adult O. volvulus, and in areas with less than 65% ivermectin coverage of the population, t...

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Hlavní autoři: deC Bronsvoort, Barend M, Makepeace, Benjamin L, Renz, Alfons, Tanya, Vincent N, Fleckenstein, Lawrence, Ekale, David, Trees, Alexander J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2008
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2464590/
https://ncbi.nlm.nih.gov/pubmed/18570639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-3305-1-18
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