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Scrapie susceptibility-linked polymorphisms modulate the in vitro conversion of sheep prion protein to protease-resistant forms

Prion diseases are natural transmissible neurodegenerative disorders in humans and animals. They are characterized by the accumulation of a protease-resistant scrapie-associated prion protein (PrP(Sc)) of the host-encoded cellular prion protein (PrP(C)) mainly in the central nervous system. Polymorp...

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Bibliografski detalji
Glavni autori: Bossers, Alex, Belt, Peter B. G. M., Raymond, Gregory J., Caughey, Byron, de Vries, Ruth, Smits, Mari A.
Format: Artigo
Jezik:Inglês
Izdano: The National Academy of Sciences of the USA 1997
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC24608/
https://ncbi.nlm.nih.gov/pubmed/9144167
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